Structure via PubChem · Public domain (PubChem)
LY293284
Sign in to saveAlso known as LY 293284, LY-293,284, LY-293284
LY-293284, also known as 4,α-methylene-5-acetyl-DPT, is a research chemical developed by the pharmaceutical company Eli Lilly and used for scientific studies. It acts as a potent and selective 5-HT1A receptor full agonist. It was derived through structural simplification of the ergoline based psychedelic LSD, but is far more selective for 5-HT1A with over 1000× selectivity over other serotonin receptor subtypes and other targets. It has anxiogenic effects in animal studies.
Chemical data
- Formula
- C19H26N2O
- Molecular weight
- 298.4 g/mol
- IUPAC name
- 1-[(4R)-4-(dipropylamino)-1,3,4,5-tetrahydrobenzo[cd]indol-6-yl]ethanone
- SMILES
- CCCN(CCC)[C@H]1CC2=CNC3=C2C(=C(C=C3)C(=O)C)C1
- InChIKey
- CKYZLYQSDNLGPT-HNNXBMFYSA-N
- XLogP
- 3.9
- Polar surface area
- 36.1 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Has part
- carbon
- Mass
- 298.204513
Show 4 more facts
- chemical formula
- C₁₉H₂₆N₂O
- isomeric SMILES
- CCCN(CCC)[C@H]1CC2=CNC3=C2C(=C(C=C3)C(=O)C)C1
- canonical SMILES
- CCCN(CCC)C1CC2=CNC3=C2C(=C(C=C3)C(=O)C)C1
- physically interacts with
- 5-hydroxytryptamine receptor 1A
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
LY-293284, also known as 4,α-methylene-5-acetyl-DPT, is a research chemical developed by the pharmaceutical company Eli Lilly and used for scientific studies. It acts as a potent and selective 5-HT1A receptor full agonist. It was derived through structural simplification of the ergoline based psychedelic LSD, but is far more selective for 5-HT1A with over 1000× selectivity over other serotonin receptor subtypes and other targets. It has anxiogenic effects in animal studies.
==See also== Partial lysergamide LY-178210 8-OH-DPAT RDS-127 RU-27849 RU-28306 N-DEAOP-NMT CT-5252
Excerpted from Wikipedia’s “LY293284” article, available under the CC BY-SA 4.0 licence.