Structure via PubChem · Public domain (PubChem)
clortermine
Sign in to saveClortermine (Voranil) was developed by Ciba in the 1960s and is an anorectic drug of the amphetamine class. It is the 2-chloro analogue of the better-known appetite suppressant phentermine and is the 2-chloro positional isomer of chlorphentermine. Clortermine produces very low rates of self-administration in animals similarly to chlorphentermine, and as a result it likely does not act on dopamine. Instead, it may act as a serotonin and/or norepinephrine releasing agent.
Chemical data
- Formula
- C10H14ClN
- Molecular weight
- 183.68 g/mol
- IUPAC name
- 1-(2-chlorophenyl)-2-methylpropan-2-amine
- SMILES
- CC(C)(CC1=CC=CC=C1Cl)N
- InChIKey
- HXCXASJHZQXCKK-UHFFFAOYSA-N
- XLogP
- 2.5
- Polar surface area
- 26 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 183.081477
Show 2 more facts
- chemical formula
- C₁₀H₁₄ClN
- canonical SMILES
- CC(C)(CC1=CC=CC=C1Cl)N
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Clortermine (Voranil) was developed by Ciba in the 1960s and is an anorectic drug of the amphetamine class. It is the 2-chloro analogue of the better-known appetite suppressant phentermine and is the 2-chloro positional isomer of chlorphentermine. Clortermine produces very low rates of self-administration in animals similarly to chlorphentermine, and as a result it likely does not act on dopamine. Instead, it may act as a serotonin and/or norepinephrine releasing agent.
== See also == 3,4-Dichloroamphetamine Cericlamine Chlorphentermine Cloforex Etolorex Methylenedioxyphentermine Phentermine
Excerpted from Wikipedia’s “clortermine” article, available under the CC BY-SA 4.0 licence.