clebopride
Clebopride is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. Chemically, it is a substituted benzamide, closely related to metoclopramide.
Chemical data
- Formula
- C20H24ClN3O2
- Molecular weight
- 373.9 g/mol
- IUPAC name
- 4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- gastrointestinal disease
via ChEMBL · EBI
Research
158 papers- Clebopride-Associated Movement Disorders.Movement disorders clinical practice · 2023
- Clebopride stimulates 5-HT(4)-serotonin receptors in the human atrium.Naunyn-Schmiedeberg's archives of pharmacology · 2025
~1 min read
Article
1 sectionsContents
- References
Clebopride is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. Chemically, it is a substituted benzamide, closely related to metoclopramide.
A small Spanish study found that more adverse reactions are reported with clebopride than with metoclopramide, particularly extrapyramidal symptoms.
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via Wikidata sitelinks · CC0