aplindore
Sign in to saveAlso known as DAB-452
Aplindore (DAB-452) is a drug which acts as a partial agonist selective for the dopamine receptor D2. It is being developed by the pharmaceutical company Neurogen as a treatment for Parkinson's disease and restless legs syndrome.
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 310.131742436
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- Commons category
- Aplindore
- canonical SMILES
- C1C(OC2=C(O1)C=CC3=C2CC(=O)N3)CNCC4=CC=CC=C4
- isomeric SMILES
- C1[C@@H](OC2=C(O1)C=CC3=C2CC(=O)N3)CNCC4=CC=CC=C4
- chemical formula
- C₁₈H₁₈N₂O₃
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Encyclopedic overview
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- See also
- References
Aplindore (DAB-452) is a drug which acts as a partial agonist selective for the dopamine receptor D2. It is being developed by the pharmaceutical company Neurogen as a treatment for Parkinson's disease and restless legs syndrome.
On December 23, 2009 Neurogen was acquired by Ligand Pharmaceuticals. Rights to Aplindore were given to Ligand around time of merger. As of 2008, Phase II was completed and Ligand.
Excerpted from Wikipedia’s “aplindore” article, available under the CC BY-SA 4.0 licence.