File:Metoclopramide.svg · Wikimedia Commons · See Wikimedia Commons
metoclopramide
Sign in to saveAlso known as metaclopromide, methochlopramide, metochlopramide, metoclopramide hydrochloride, Reglan®, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide, 4-amino-5-chloro-2-methoxy-N-(beta-diethylaminoethyl)benzamide
Metoclopramide is a medication used to treat nausea, vomiting, gastroparesis, and gastroesophageal reflux disease. It is also used to treat migraine headaches.
Key facts
- Drug.ATC_suffix
- FA01
- Drug.legal_AU
- S4
- Drug.H
- 22
- Drug.Cl
- 1
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 464194334
- Drug.image
- Metoclopramide.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 200
- Drug.image2
- Metoclofinal.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 200
- Drug.tradename
- Primperan, others
- Drug.MedlinePlus
- a684035
- Drug.DailyMedID
- Metoclopramide
- Drug.pregnancy_AU
- A
- Drug.routes_of_administration
- By mouth, intravenous, intramuscular, nasal spray
- Drug.class
- D2 receptor antagonist; 5-HT3 receptor antagonist; 5-HT4 receptor agonist; Prolactin releaser
via Wikipedia infobox
Chemical data
- Formula
- C14H22ClN3O2
- Molecular weight
- 299.79 g/mol
- IUPAC name
- 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
- SMILES
- CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Cl
- InChIKey
- TTWJBBZEZQICBI-UHFFFAOYSA-N
- XLogP
- 2.6
- Polar surface area
- 67.6 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
~16 min read
Encyclopedic overview
21 sectionsContents
- Medical uses
- Nausea
- Migraine
- Gastroparesis
- Lactation
- Procedures
- Contraindications
- Pregnancy
- Infants
- Side effects
- Rare side effects
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Chemistry
- History
- Society and culture
- Brand names
- Veterinary use
- References
- External links
Metoclopramide is a medication used to treat nausea, vomiting, gastroparesis, and gastroesophageal reflux disease. It is also used to treat migraine headaches.
Common side effects include feeling tired, diarrhea, and akathisia. More serious side effects include neuroleptic malignant syndrome, tardive dyskinesia, and depression. It is thus rarely recommended that people take the medication for longer than twelve weeks. No evidence of harm has been found after being taken by many pregnant women. It belongs to the group of medications known as dopamine receptor antagonists and works as a prokinetic.
Excerpted from Wikipedia’s “metoclopramide” article, available under the CC BY-SA 4.0 licence.