PROKR1
Sign in to saveAlso known as GPR73, GPR73a, PKR1, ZAQ, prokineticin receptor 1, PK-R1
protein-coding gene in the species Homo sapiens
Gene data
PROKR1- Name
- prokineticin receptor 1
- Type
- protein-coding
- Position
- 68,643,086–68,659,042 (+)
- Aliases
- GPR73, GPR73a, PK-R1, PKR1, ZAQ
- Ensembl
- ENSG00000169618
- RefSeq RNA
- NM_138964.4
- RefSeq protein
- NP_620414.1
This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
prokineticin receptor 1
- Symbol
- PROKR1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:68,643,086-68,659,042
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 10968
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10887
- cytogenetic location
- 2p13.3
- chromosome
- human chromosome 2
- genomic start
- 68643579
- genomic end
- 68658251
- expressed in
- hypothalamus
Sources (3)
via Wikidata · CC0