Also known as ARFL1, ADP ribosylation factor like GTPase 1
ADP-ribosylation factor-like protein 1 is a protein that in humans is encoded by the ARL1 gene.
The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014].
Biological process
~1 min read
ADP-ribosylation factor-like protein 1 is a protein that in humans is encoded by the ARL1 gene.
== Function ==
via MyGene.info
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).