arsthinol
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Arsthinol (INN) is an organoarsenic compound with the formula . A antiprotozoal agent, it was first reported in 1949. It arises by the reaction of acetarsol with 2,3-dimercaptopropanol (British anti-Lewisite) and has been demonstrated to be effective against amoebiasis and yaws. It was marketed a few years later by Endo Products (Balarsen, Tablets, 0.1 g).
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 346.9631068080001
- Has use
- medication
Show 2 more facts
- chemical formula
- C₁₁H₁₄AsNO₃S₂
- canonical SMILES
- CC(=O)NC1=CC(=CC=C1O)[As]1SCC(CO)S1
Sources (2)
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Encyclopedic overview
2 sectionsContents
- Properties
- References
{{chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 457817818 | ImageFile = Arsthinol.svg | ImageClass = skin-invert-image | ImageFile_Ref = | ImageSize = 244 | ImageName = Structural formula of arsthinol | PIN = N-{2-Hydroxy-5-[4-(hydroxymethyl)-1,3,2-dithiarsolan-2-yl]phenyl}acetamide |Section1= |Section2= |Section6= }} Arsthinol (INN) is an organoarsenic compound with the formula . A antiprotozoal agent, it was first reported in 1949. It arises by the reaction of acetarsol with 2,3-dimercaptopropanol (British anti-Lewisite) and has been demonstrated to be effective against amoebiasis and yaws. It was marketed a few years later by Endo Products (Balarsen, Tablets, 0.1 g).
Among trivalent organoarsenicals, arsthinol was considered very well tolerated. Recently, it was studied for its anticancer activity.
Excerpted from Wikipedia’s “arsthinol” article, available under the CC BY-SA 4.0 licence.
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