chlorquinaldol
Sign in to saveAlso known as 5,7-dichloro-2-methyl-8-hydroxyquinoline, 5,7-dichloro-2-methyl-8-quinolinol, 2-methyl-5,7-dichloro-8-hydroxyquinoline, 5,7-dichloro-8-hydroxy-2-methylquinoline, 5,7-dichloro-8-quinaldinol, 5,7-dichloro-8-hydroxyquinaldine
Chlorquinaldol is an antimicrobial agent and antiseptic. It is a chlorinated derivative of the popular chelating agent 8-hydroxyquinoline. It is applied topically as a cream and internally as a losenge.
Research
145 papers- Chlorquinaldol Alleviates Lung Fibrosis in Mice by Inhibiting Fibroblast Activation through Targeting Methionine Synthase Reductase.ACS central science · 2024
- Chlorquinaldol targets the β-catenin and T-cell factor 4 complex and exerts anti-colorectal cancer activity.Pharmacological research · 2020
- Chlorquinaldol, a topical agent for skin and wound infections: anti-biofilm activity and biofilm-related antimicrobial cross-resistance.Infection and drug resistance · 2019
- Chlorquinaldol inhibits the activation of nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing protein 3 inflammasome and ameliorates imiquimod-induced psoriasis-like dermatitis in mice.Chemico-biological interactions · 2022
- Antimycotic effect of chlorquinaldol.Transactions of the New York Academy of Sciences · 1955
via PubMed
Wikidata facts
- Mass
- 226.99
Show 5 more facts
- chemical formula
- C₁₀H₇Cl₂NO
- canonical SMILES
- CC1=NC2=C(C=C1)C(=CC(=C2O)Cl)Cl
- World Health Organisation international non-proprietary name
- chlorquinaldol
- Commons category
- Chlorquinaldol
- defined daily dose
- 0.2
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Article
1 sectionsContents
- References
Chlorquinaldol is an antimicrobial agent and antiseptic. It is a chlorinated derivative of the popular chelating agent 8-hydroxyquinoline. It is applied topically as a cream and internally as a losenge.
It was marketed by Geigy as an intestinal antiseptic and amebicide with the trade name Siosteran.
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