Structure via PubChem · Public domain (PubChem)
fenticlor
Sign in to saveAlso known as 2,2'-Thiobis4-chlorophenol, 2,2'-Dihydroxy-5,5'-dichlorodiphenyl sulfide, Bis(2-hydroxy-5-chlorophenyl) sulfide, Fentichlor, 2,2'-Thiobis(4-chlorophenol), Bis(2-hydroxy-5-chlorophenyl)sulfide, Phentichlorum, 5,5'-Dichloro-2,2'-dihydroxydiphenyl sulfide
Fenticlor (also spelled fentichlor) is an antibacterial and antifungal agent for topical use. It is an antimicrobial agent. It is also used in veterinary medicine. __TOC__ ==Synthesis== It is prepared by the AlCl3-catalyzed reaction of 4-chlorophenol with sulfur dichloride. It can also be prepared by chlorination of bis[2-hydroxyphenyl]sulfide.
Chemical data
- Formula
- C12H8Cl2O2S
- Molecular weight
- 287.2 g/mol
- IUPAC name
- 4-chloro-2-(5-chloro-2-hydroxyphenyl)sulfanylphenol
- SMILES
- C1=CC(=C(C=C1Cl)SC2=C(C=CC(=C2)Cl)O)O
- InChIKey
- ANUSOIHIIPAHJV-UHFFFAOYSA-N
- XLogP
- 4.5
- Polar surface area
- 65.8 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 285.962
Show 3 more facts
- chemical formula
- C₁₂H₈Cl₂O₂S
- canonical SMILES
- C1=CC(=C(C=C1Cl)SC2=C(C=CC(=C2)Cl)O)O
- World Health Organisation international non-proprietary name
- fenticlor
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- Safety
- References
Fenticlor (also spelled fentichlor) is an antibacterial and antifungal agent for topical use. It is an antimicrobial agent. It is also used in veterinary medicine. __TOC__ ==Synthesis== It is prepared by the AlCl3-catalyzed reaction of 4-chlorophenol with sulfur dichloride. It can also be prepared by chlorination of bis[2-hydroxyphenyl]sulfide.
==Safety== The (rats, oral) of fenticlor is 3250 mg/kg. It may cause photosensitivity.
Excerpted from Wikipedia’s “fenticlor” article, available under the CC BY-SA 4.0 licence.