BLMH
Sign in to saveAlso known as BH, BMH, bleomycin hydrolase
protein-coding gene in the species Homo sapiens
Gene data
BLMH- Name
- bleomycin hydrolase
- Type
- protein-coding
- Position
- 30,248,193–30,292,152 (−)
- Aliases
- BH, BMH
- Ensembl
- ENSG00000108578
- RefSeq RNA
- NM_000386.4
- RefSeq protein
- NP_000377.1
Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
bleomycin hydrolase
- Symbol
- BLMH
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:30,248,193-30,292,152
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein BLMH PDB 1cb5.png
Show 7 more facts
- HomoloGene ID
- 330
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/642
- genomic end
- 28619074
- genomic start
- 30248203
- chromosome
- human chromosome 17
- cytogenetic location
- 17q11.2
Sources (3)
via Wikidata · CC0