BLMH
Sign in to saveAlso known as BH, BMH, bleomycin hydrolase
protein-coding gene in the species Homo sapiens
Gene data
BLMH- Name
- bleomycin hydrolase
- Type
- protein-coding
- Position
- 30,248,200–30,292,152 (−)
- Aliases
- BH, BMH
- Ensembl
- ENSG00000108578
- RefSeq RNA
- NM_000386.4
- RefSeq protein
- NP_000377.1
Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
bleomycin hydrolase
- Symbol
- BLMH
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:30,248,193-30,292,152
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein BLMH PDB 1cb5.png
Show 5 more facts
- HomoloGene ID
- 330
- exact match
- identifiers.org/ncbigene/642
- genomic end
- 28619074
- genomic start
- 30248203
- cytogenetic location
- 17q11.2
Sources (3)
via Wikidata · CC0
Connections
Q180686
Entity
human chromosome 17
Entity
Ensembl genome database project
Entity
enzyme
Entity
Wikidata
Entity
gene
Entity
chromosome
Entity
digital object identifier
Entity
International Standard Serial Number
Entity
bibcode
Entity
human genome
Entity
Q229883
Entity
base pair
Entity
locus
Entity
gene expression
Entity
Online Mendelian Inheritance in Man
Entity
cofactor
Entity
ligases
Entity
peptidase
Entity
Enzyme Commission number
Entity