CBX2
Sign in to saveAlso known as M33, CDCA6, SRXY5, chromobox 2
protein-coding gene in the species Homo sapiens
Gene data
CBX2- Name
- chromobox 2
- Type
- protein-coding
- Aliases
- CDCA6, M33, SRXY5
This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2010].
via MyGene.info
Gene · Ensembl
chromobox 2
- Symbol
- CBX2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:79,778,135-79,788,394
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CBX2 PDB 2d9u.png
Show 5 more facts
- exact match
- identifiers.org/ncbigene/84733
- HomoloGene ID
- 7256
- genomic start
- 79778148
- genomic end
- 77761782
- cytogenetic location
- 17q25.3
Sources (4)
via Wikidata · CC0
Connections
Q180686
Entity
human chromosome 17
Entity
Ensembl genome database project
Entity
protein
Entity
Wikidata
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gene
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chromosome
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digital object identifier
Entity
bibcode
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human genome
Entity
Q229883
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base pair
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locus
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gene expression
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Online Mendelian Inheritance in Man
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Protein Data Bank
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Q22908627
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New Scientist
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Entrez
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Q905695
Entity