CBX2
Sign in to saveAlso known as M33, CDCA6, SRXY5, chromobox 2
protein-coding gene in the species Homo sapiens
Gene data
CBX2- Name
- chromobox 2
- Type
- protein-coding
- Position
- 79,778,135–79,788,394 (+)
- Aliases
- CDCA6, M33, SRXY5
- Ensembl
- ENSG00000173894
- RefSeq RNA
- NM_005189.3, NM_032647.4, XM_011525382.2, XM_011525383.3, XM_047436946.1
- RefSeq protein
- NP_005180.1, NP_116036.1, XP_011523684.1, XP_011523685.1, XP_047292902.1
This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
chromobox 2
- Symbol
- CBX2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:79,778,135-79,788,394
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CBX2 PDB 2d9u.png
Show 7 more facts
- exact match
- identifiers.org/ncbigene/84733
- HomoloGene ID
- 7256
- found in taxon
- Homo sapiens
- chromosome
- human chromosome 17
- genomic start
- 79778148
- genomic end
- 77761782
- cytogenetic location
- 17q25.3
Sources (4)
via Wikidata · CC0