CDON

Also known as CDO, CDON1, HPE11, ORCAM, cell adhesion associated, oncogene regulated, Ihog

Cell adhesion molecule-related/down-regulated by oncogenes is a protein that in humans is encoded by the CDON gene.

Gene data

CDON

Name: cell adhesion associated, oncogene regulated
Type: protein-coding
Aliases: CDO, CDON1, HPE11, Ihog, ORCAM

This gene encodes a cell surface receptor that is a member of the immunoglobulin superfamily. The encoded protein contains three fibronectin type III domains and five immunoglobulin-like C2-type domains. This protein is a member of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells and positively regulates myogenesis. [provided by RefSeq, Aug 2011].

via MyGene.info

Gene · Ensembl

cell adhesion associated, oncogene regulated

Symbol: CDON
Biotype: Protein coding
Organism: Homo sapiens
Location: 11:125,955,796-126,063,335
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein CDON PDB 3D1M.png

Show 5 more facts

HomoloGene ID: 22996
exact match: identifiers.org/ncbigene/50937
genomic end: 125933230
genomic start: 125825691
cytogenetic location: 11q24.2

Sources (4)

via Wikidata · CC0

~3 min read

Article

7 sections

Contents

Structure and function
Clinical significance
Gene knockdown studies
Interactions
References
Further reading
External links

Cell adhesion molecule-related/down-regulated by oncogenes is a protein that in humans is encoded by the CDON gene.

CDON and BOC are cell surface receptors of the immunoglobulin (Ig)/fibronectin type III (FNIII) repeat family involved in myogenic differentiation. CDON and BOC are coexpressed during development, form complexes with each other in a cis fashion, and are related to each other in their ectodomains, but each has a unique long cytoplasmic tail.