CHAF1B
Sign in to saveAlso known as CAF-1, CAF-IP60, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7, chromatin assembly factor 1 subunit B
Chromatin assembly factor 1 subunit B is a protein that in humans is encoded by the CHAF1B gene.
Gene data
CHAF1B- Name
- chromatin assembly factor 1 subunit B
- Type
- protein-coding
- Position
- 36,385,354–36,419,015 (+)
- Aliases
- CAF-1, CAF-IP60, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7
- Ensembl
- ENSG00000159259
- RefSeq RNA
- NM_005441.3, XM_047441000.1, XM_054324876.1
- RefSeq protein
- NP_005432.1, XP_047296956.1, XP_054180851.1
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
chromatin assembly factor 1 subunit B
- Symbol
- CHAF1B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 21:36,385,354-36,419,015
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 48346
- exact match
- identifiers.org/ncbigene/8208
- genomic end
- 37791313
- genomic start
- 36385392
- cytogenetic location
- 21q22.12-q22.13
Sources (3)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Interactions
- References
- Further reading
- External links
Chromatin assembly factor 1 subunit B is a protein that in humans is encoded by the CHAF1B gene.
== Function ==