CHD5

Also known as CHD-5, chromodomain helicase DNA binding protein 5, PMNDS

Chromodomain-helicase-DNA-binding protein 5 is an enzyme that in humans is encoded by the CHD5 gene. It is a part of the CHD subfamily of ATP-dependent chromatin remodeling complexes.

Gene data

CHD5

Name: chromodomain helicase DNA binding protein 5
Type: protein-coding
Position: 6,101,787–6,180,321 (−)
Aliases: CHD-5, PMNDS
Ensembl: ENSG00000116254
RefSeq RNA: NM_015557.3
RefSeq protein: NP_056372.1

This gene encodes a member of the chromodomain helicase DNA-binding protein family. Members of this family are characterized by a chromodomain, a helicase ATP-binding domain and an additional functional domain. This gene encodes a neuron-specific protein that may function in chromatin remodeling and gene transcription. This gene is a potential tumor suppressor gene that may play a role in the development of neuroblastoma. [provided by RefSeq, Feb 2012].

Gene Ontology

Biological process

negative regulation of transcription by RNA polymerase II chromatin remodeling

Article

3 sections

Contents

References
External links
Further reading

Chromodomain-helicase-DNA-binding protein 5 is an enzyme that in humans is encoded by the CHD5 gene. It is a part of the CHD subfamily of ATP-dependent chromatin remodeling complexes.

==References==