CHD7

Also known as CRG, HH5, IS3, KAL5, chromodomain helicase DNA binding protein 7

Chromodomain-helicase-DNA-binding protein 7 is an ATP-dependent 'chromatin' or 'nucleosome' remodeling factor that in humans is encoded by the CHD7 gene.

Gene data

CHD7

Name: chromodomain helicase DNA binding protein 7
Type: protein-coding
Aliases: CRG, HH5, IS3, KAL5

This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015].

via MyGene.info

Gene · Ensembl

chromodomain helicase DNA binding protein 7

Symbol: CHD7
Biotype: Protein coding
Organism: Homo sapiens
Location: 8:60,678,715-60,868,031
Strand: Forward (+)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Image: PDB 2ckc EBI.png

Show 6 more facts

HomoloGene ID: 19067
exact match: identifiers.org/ncbigene/55636
genomic start: 60678740
genomic end: 61779465
cytogenetic location: 8q12.2
Commons category: Chromodomain-helicase-DNA-binding protein 7

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Chromodomain-helicase-DNA-binding protein 7 is an ATP-dependent 'chromatin' or 'nucleosome' remodeling factor that in humans is encoded by the CHD7 gene.

CHD7 is an ATP-dependent chromatin remodeler homologous to the Drosophila trithorax-group protein Kismet. Mutations in CHD7 are associated with CHARGE syndrome. This protein belongs to a larger group of ATP-dependent chromatin remodeling complexes, the CHD subfamily.