CHKB

Name

choline kinase beta

Type

protein-coding

Position

50,578,959–50,601,455 (−)

Aliases

CHETK, CHKL, CK, CKB, CKEKB, EK, EKB, MDCMC

Ensembl

ENSG00000100288

RefSeq RNA

NM_005198.5, NM_152253.1

RefSeq protein

NP_005189.2

Choline kinase (CK) and ethanolamine kinase (EK) catalyze the phosphorylation of choline/ethanolamine to phosphocholine/phosphoethanolamine. This is the first enzyme in the biosynthesis of phosphatidylcholine/phosphatidylethanolamine in all animal cells. The highly purified CKs from mammalian sources and their recombinant gene products have been shown to have EK activity also, indicating that both activities reside on the same protein. The choline kinase-like protein encoded by CHKL belongs to the choline/ethanolamine kinase family; however, its exact function is not known. Read-through transcripts are expressed from this locus that include exons from the downstream CPT1B locus. [provided by RefSeq, Jun 2009].

via MyGene.info

Gene · Ensembl

choline kinase beta

Symbol

CHKB

Biotype

Protein coding

Organism

Homo sapiens

Location

22:50,578,959-50,601,455

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein CHKB PDB 2ig7.png

via Wikidata · CC0