CHMP5
Sign in to saveAlso known as C9orf83, HSPC177, PNAS-2, SNF7DC2, Vps60, CGI-34, charged multivesicular body protein 5
Charged multivesicular body protein 5 is a protein that in humans is encoded by the CHMP5 gene.
Gene data
CHMP5- Name
- charged multivesicular body protein 5
- Type
- protein-coding
- Position
- 33,264,017–33,282,071 (+)
- Aliases
- C9orf83, CGI-34, HSPC177, PNAS-2, SNF7DC2, Spike, Vps60
- Ensembl
- ENSG00000086065
- RefSeq RNA
- NM_001195536.2, NM_016410.6
- RefSeq protein
- NP_001182465.1, NP_057494.3
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Wikidata facts
Show 3 more facts
- HomoloGene ID
- 5757
- exact match
- identifiers.org/ncbigene/51510
- cytogenetic location
- 9p13.3
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- References
- External links
- Further reading
Charged multivesicular body protein 5 is a protein that in humans is encoded by the CHMP5 gene.
== Function ==