CLDN2
Sign in to saveAlso known as claudin 2, OAZON
Claudin-2 is a protein that in humans is encoded by the CLDN2 gene. It belongs to the group of claudins.
Gene data
CLDN2- Name
- claudin 2
- Type
- protein-coding
- Chromosome
- X
- Position
- 106,892,766–106,930,862 (+)
- Aliases
- OAZON, claudin-2
- Ensembl
- ENSG00000165376
- RefSeq RNA
- NM_001171092.1, NM_001171095.2, NM_020384.4, XM_054328084.1, XM_054328085.1
- RefSeq protein
- NP_001164563.1, NP_001164566.1, NP_065117.1, XP_054184059.1, XP_054184060.1
This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
claudin 2
- Symbol
- CLDN2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:106,892,766-106,930,862
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 9621
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9075
- chromosome
- human X chromosome
- genomic start
- 106143394
- genomic end
- 106174091
- cytogenetic location
- Xq22.3
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- References
- External links
- Further reading
Claudin-2 is a protein that in humans is encoded by the CLDN2 gene. It belongs to the group of claudins.
Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions (Sakaguchi et al., 2002).[supplied by OMIM]
Excerpted from Wikipedia’s “CLDN2” article, available under the CC BY-SA 4.0 licence.