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CLIC or Clic can refer to:
== Science and Technology == Chloride intracellular channel (a type of chloride channel, consists of six conserved proteins in humans (CLIC1, CLIC2, CLIC3, CLIC4, CLIC5, CLIC6) Clathrin-independent carrier (a subtype of endocytic membrane) Compact Linear Collider, a proposed particle accelerator at CERN