CLIC2

Also known as CLIC2b, MRXS32, XAP121, chloride intracellular channel 2, CLCNL2

Chloride intracellular channel protein 2 is a protein that in humans is encoded by the CLIC2 gene.

Gene data

CLIC2

Name: CLIC family member 2
Type: protein-coding
Chromosome: X
Aliases: CLCNL2, CLIC2b, MRXS32, XAP121

This gene encodes a chloride intracellular channel protein. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. This protein plays a role in inhibiting the function of ryanodine receptor 2. A mutation in this gene is the cause of an X-linked form of cognitive disability. [provided by RefSeq, Jul 2017].

via MyGene.info

Gene · Ensembl

chloride intracellular channel 2

Symbol: CLIC2
Biotype: Protein coding
Organism: Homo sapiens
Location: Chr X:155,272,944-155,334,824
Strand: Reverse (−)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein CLIC2 PDB 2PER.png

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HomoloGene ID: 48010
exact match: identifiers.org/ncbigene/1193
genomic start: 154505500
genomic end: 154563966
cytogenetic location: Xq28

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Chloride intracellular channel protein 2 is a protein that in humans is encoded by the CLIC2 gene.

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 2 is a member of the p64 family; the protein is detected in fetal liver and adult skeletal muscle tissue. This gene maps to the candidate region on chromosome X for incontinentia pigmenti.