TRPM7
Sign in to saveAlso known as ALSPDC, CHAK, CHAK1, LTRPC7, LTrpC-7, TRP-PLIK, transient receptor potential cation channel subfamily M member 7
Transient receptor potential cation channel, subfamily M, member 7, also known as TRPM7, is a human gene encoding a protein of the same name.
Gene data
TRPM7- Name
- transient receptor potential cation channel subfamily M member 7
- Type
- protein-coding
- Position
- 50,552,473–50,686,845 (−)
- Aliases
- ALSPDC, CHAK, CHAK1, LTRPC7, LTrpC-7, TRP-PLIK
- Ensembl
- ENSG00000092439
- RefSeq RNA
- NM_001301212.2, NM_017672.6, NR_149152.2, NR_149153.2, NR_149154.2
- RefSeq protein
- NP_001288141.1, NP_060142.3
This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function. [provided by RefSeq, Aug 2017].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
transient receptor potential cation channel subfamily M member 7
- Symbol
- TRPM7
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:50,552,473-50,686,845
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein TRPM7 PDB 1ia9.png
Show 9 more facts
- HomoloGene ID
- 9774
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/54822
- genomic end
- 50686797
- genomic start
- 50844670
- chromosome
- human chromosome 15
- cytogenetic location
- 15q21.2
- genetic association
- Lytico-bodig disease
- Commons category
- TRPM7
via Wikidata · CC0
~1 min read
Encyclopedic overview
7 sectionsContents
- Function
- Interactions
- Clinical relevance
- See also
- References
- Further reading
- External links
Transient receptor potential cation channel, subfamily M, member 7, also known as TRPM7, is a human gene encoding a protein of the same name.
== Function ==
Excerpted from Wikipedia’s “TRPM7” article, available under the CC BY-SA 4.0 licence.