HCN1
Sign in to saveAlso known as BCNG-1, BCNG1, EIEE24, HAC-2, hyperpolarization activated cyclic nucleotide gated potassium channel 1, GEFSP10, DEE24
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 is a protein that in humans is encoded by the HCN1 gene.
Gene data
HCN1- Name
- hyperpolarization activated cyclic nucleotide gated potassium channel 1
- Type
- protein-coding
- Position
- 45,254,948–45,696,498 (−)
- Aliases
- BCNG-1, BCNG1, DEE24, EIEE24, GEFSP10, HAC-2
- Ensembl
- ENSG00000164588
- RefSeq RNA
- NM_021072.4
- RefSeq protein
- NP_066550.2
The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for sour tastes. [provided by RefSeq, Oct 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
hyperpolarization activated cyclic nucleotide gated potassium channel 1
- Symbol
- HCN1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:45,254,948-45,696,498
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- 5u6p.jpg
Show 9 more facts
- HomoloGene ID
- 32093
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/348980
- genomic start
- 45254948
- chromosome
- human chromosome 5
- genomic end
- 45696253
- cytogenetic location
- 5p12
- expressed in
- parietal lobe
- Commons category
- HCN1 channel
via Wikidata · CC0
~1 min read
Encyclopedic overview
9 sectionsContents
- Function
- Tissue distribution
- Ligands
- Interactions
- Epilepsy
- See also
- References
- Further reading
- External links
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 is a protein that in humans is encoded by the HCN1 gene.
== Function ==
Excerpted from Wikipedia’s “HCN1” article, available under the CC BY-SA 4.0 licence.