ITPR3
Sign in to saveAlso known as IP3R, IP3R3, inositol 1,4,5-trisphosphate receptor type 3
Inositol 1,4,5-trisphosphate receptor, type 3, also known as ITPR3, is a protein which in humans is encoded by the ITPR3 gene. The protein encoded by this gene is both a receptor for inositol triphosphate and a calcium channel.
Gene data
ITPR3- Name
- inositol 1,4,5-trisphosphate receptor type 3
- Type
- protein-coding
- Aliases
- CMT1J, IMD132, IMD133, IP3R, IP3R-3, IP3R3
This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. [provided by RefSeq, Aug 2010].
via MyGene.info
Gene · Ensembl
inositol 1,4,5-trisphosphate receptor type 3
- Symbol
- ITPR3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:33,620,331-33,696,575
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- IP3 receptor type 3 (ITPR3) - 6DQN.png
Show 6 more facts
- HomoloGene ID
- 1675
- exact match
- identifiers.org/ncbigene/3710
- genomic end
- 33664351
- genomic start
- 33588142
- cytogenetic location
- 6p21.31
- Commons category
- ITPR3
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- See also
- References
- Further reading
- External links
Inositol 1,4,5-trisphosphate receptor, type 3, also known as ITPR3, is a protein which in humans is encoded by the ITPR3 gene. The protein encoded by this gene is both a receptor for inositol triphosphate and a calcium channel.
== Function ==