TMC2
Sign in to saveAlso known as C20orf145, dJ686C3.3, transmembrane channel like 2
Transmembrane channel-like protein 2 is a protein that in humans is encoded by the TMC2 gene.
Gene data
TMC2- Name
- transmembrane channel like 2
- Type
- protein-coding
- Position
- 2,536,573–2,643,580 (+)
- Aliases
- C20orf145
- Ensembl
- ENSG00000149488
- RefSeq RNA
- NM_080751.3, XM_005260660.5, XM_054322937.1, XR_001754152.2, XR_008485230.1
- RefSeq protein
- NP_542789.2, XP_005260717.1, XP_054178912.1
This gene encodes a transmembrane protein that is necesssary for mechanotransduction in cochlear hair cells of the inner ear. Mutations in this gene may underlie hereditary disorders of balance and hearing. [provided by RefSeq, Aug 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
transmembrane channel like 2
- Symbol
- TMC2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:2,536,573-2,643,580
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 25877
- exact match
- identifiers.org/ncbigene/117532
- genomic end
- 2643580
- genomic start
- 2536573
- cytogenetic location
- 20p13
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
Transmembrane channel-like protein 2 is a protein that in humans is encoded by the TMC2 gene.
== Function ==
Connections
Q180686
Entity
human chromosome 20
Entity
Ensembl genome database project
Entity
protein
Entity
Wikidata
Entity
gene
Entity
chromosome
Entity
digital object identifier
Entity
hearing
Entity
bibcode
Entity
genetic disease
Entity
human genome
Entity
Q229883
Entity
base pair
Entity
locus
Entity
gene expression
Entity
Online Mendelian Inheritance in Man
Entity
Q22908627
Entity
transmembrane protein
Entity
Entrez
Entity