TMX1

Name

thioredoxin related transmembrane protein 1

Type

protein-coding

Position

51,240,152–51,259,059 (+)

Aliases

PDIA11, TMX, TXNDC, TXNDC1

Ensembl

ENSG00000139921

RefSeq RNA

NM_030755.5

RefSeq protein

NP_110382.3

This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides. [provided by RefSeq, Jan 2017].

via MyGene.info

Gene · Ensembl

thioredoxin related transmembrane protein 1

Symbol

TMX1

Biotype

Protein coding

Organism

Homo sapiens

Location

14:51,240,152-51,259,059

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein TXNDC1 PDB 1x5e.png

via Wikidata · CC0