TMTC2
Sign in to saveAlso known as IBDBP1, transmembrane and tetratricopeptide repeat containing 2, transmembrane O-mannosyltransferase targeting cadherins 2
Transmembrane and TPR repeat-containing protein 2 is a protein that in humans is encoded by the TMTC2 gene.
In the Vinony graph
Within Vinony's link graph, TMTC2 is referenced by 4 other articles, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 12.
Its subject is documented across 5 Wikipedia language editions.
Gene data
TMTC2- Name
- transmembrane O-mannosyltransferase targeting cadherins 2
- Type
- protein-coding
- Position
- 82,686,880–83,134,870 (+)
- Aliases
- IBDBP1
- Ensembl
- ENSG00000179104
- RefSeq RNA
- NM_001320321.2, NM_001320322.2, NM_152588.3, XM_017018884.3, XM_024448863.2
- RefSeq protein
- NP_001307250.1, NP_001307251.1, NP_689801.1, XP_016874373.1, XP_024304631.1
The protein encoded by this gene is an integral membrane protein localized to the endoplasmic reticulum (ER). The encoded protein contains many tetratricopeptide repeats, sequences known for being involved in protein-protein interactions. This protein binds both the calcium uptake pump SERCA2B and the carbohydrate-binding chaperone calnexin, and it appears to play a role in calcium homeostasis in the ER. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
transmembrane O-mannosyltransferase targeting cadherins 2
- Symbol
- TMTC2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:82,686,880-83,134,870
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 25521
- exact match
- identifiers.org/ncbigene/160335
- genetic association
- prostate cancer
- found in taxon
- Homo sapiens
- genomic end
- 83528649
- genomic start
- 83080659
- chromosome
- human chromosome 12
- cytogenetic location
- 12q21.31
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Transmembrane and TPR repeat-containing protein 2 is a protein that in humans is encoded by the TMTC2 gene.
==References==
Excerpted from Wikipedia’s “TMTC2” article, available under the CC BY-SA 4.0 licence.