CLSTN1

Name

calsyntenin 1

Type

protein-coding

Position

9,728,911–9,823,993 (−)

Aliases

ALC-ALPHA, CDHR12, CST-1, CSTN1, XB31alpha, alcalpha1, alcalpha2

Ensembl

ENSG00000171603

RefSeq RNA

NM_001009566.3, NM_001302883.1, NM_014944.4, XM_047449470.1, XM_054335191.1

RefSeq protein

NP_001009566.1, NP_001289812.1, NP_055759.3, XP_047305426.1, XP_054191166.1

This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014].

via MyGene.info

Gene · Ensembl

calsyntenin 1

Symbol

CLSTN1

Biotype

Protein coding

Organism

Homo sapiens

Location

1:9,728,911-9,823,993

Strand

Reverse (−)

Assembly

GRCh38