APBA2
Sign in to saveAlso known as D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L, amyloid beta precursor protein binding family A member 2
Amyloid beta A4 precursor protein-binding family A member 2 is a protein that in humans is encoded by the APBA2 gene.
Gene data
APBA2- Name
- amyloid beta precursor protein binding family A member 2
- Type
- protein-coding
- Aliases
- D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2017].
via MyGene.info
Gene · Ensembl
amyloid beta precursor protein binding family A member 2
- Symbol
- APBA2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:28,884,449-29,118,317
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein APBA1 PDB 1u39.png
Show 6 more facts
- HomoloGene ID
- 4021
- exact match
- identifiers.org/ncbigene/321
- genomic start
- 29129629
- genomic end
- 29410518
- Commons category
- APBA2
- cytogenetic location
- 15q13.1
Sources (3)
via Wikidata · CC0
~1 min read
Article
6 sectionsContents
- Structure
- Function
- Interactions
- References
- External links
- Further reading
Amyloid beta A4 precursor protein-binding family A member 2 is a protein that in humans is encoded by the APBA2 gene.
== Structure ==