APBB2
Sign in to saveAlso known as FE65L, FE65L1, amyloid beta precursor protein binding family B member 2
Amyloid beta A4 precursor protein-binding family B member 2 is a protein that in humans is encoded by the APBB2 gene.
Gene data
APBB2- Name
- amyloid beta precursor protein binding family B member 2
- Type
- protein-coding
- Position
- 40,810,027–41,216,714 (−)
- Aliases
- FE65L, FE65L1
- Ensembl
- ENSG00000163697
- RefSeq RNA
- NM_001166050.2, NM_001166051.2, NM_001166052.2, NM_001166053.1, NM_001166054.1
- RefSeq protein
- NP_001159522.1, NP_001159523.1, NP_001159524.1, NP_001159525.1, NP_001159526.1
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
Gene Ontology
Biological process
via MyGene.info
Gene · Ensembl
amyloid beta precursor protein binding family B member 2
- Symbol
- APBB2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:40,810,027-41,216,714
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein APBB2 PDB 1wgu.png
Show 5 more facts
- HomoloGene ID
- 32079
- exact match
- identifiers.org/ncbigene/323
- genomic end
- 41218731
- genomic start
- 40812044
- cytogenetic location
- 4p14-p13
via Wikidata · CC0
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Article
3 sectionsContents
- References
- External links
- Further reading
Amyloid beta A4 precursor protein-binding family B member 2 is a protein that in humans is encoded by the APBB2 gene.
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction.