APBA1

Name

amyloid beta precursor protein binding family A member 1

Type

protein-coding

Chromosome

HSCHR9_1_CTG2

Position

21,985–70,597 (−)

Aliases

D9S411E, LIN10, MINT1, X11, X11A, X11ALPHA

Ensembl

ENSG00000276497

RefSeq RNA

NM_001163.4, XM_005251968.4, XM_011518617.3, XM_017014670.2, XM_047423300.1

RefSeq protein

NP_001154.2, XP_005252025.1, XP_011516919.1, XP_016870159.1, XP_047279256.1

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

amyloid beta precursor protein binding family A member 1

Symbol

APBA1

Biotype

Protein coding

Organism

Homo sapiens

Location

9:69,427,532-69,672,392

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein APBA1 PDB 1aqc.png

via Wikidata · CC0