APPBP2

Also known as APP-BP2, HS.84084, PAT1, amyloid beta precursor protein binding protein 2

Amyloid protein-binding protein 2 is a protein that in humans is encoded by the APPBP2 gene.

Gene data

APPBP2

Name: amyloid beta precursor protein binding protein 2
Type: protein-coding
Position: 60,443,158–60,526,242 (−)
Aliases: APP-BP2, HS.84084, PAT1
Ensembl: ENSG00000062725
RefSeq RNA: NM_001282476.2, NM_006380.5, XM_047435116.1, XM_047435118.1, XM_054314702.1
RefSeq protein: NP_001269405.1, NP_006371.2, XP_047291072.1, XP_047291074.1, XP_054170677.1

The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013].

via MyGene.info

Gene · Ensembl

amyloid beta precursor protein binding protein 2

Symbol: APPBP2
Biotype: Protein coding
Organism: Homo sapiens
Location: 17:60,443,158-60,526,242
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 31378
exact match: identifiers.org/ncbigene/10513
genomic end: 60526242
genomic start: 60443158
cytogenetic location: 17q23.2

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Amyloid protein-binding protein 2 is a protein that in humans is encoded by the APPBP2 gene.

The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene.