APPBP2
Sign in to saveAlso known as APP-BP2, HS.84084, PAT1, amyloid beta precursor protein binding protein 2
Amyloid protein-binding protein 2 is a protein that in humans is encoded by the APPBP2 gene.
In the Vinony graph
Vinony's link graph records 2 inbound references to APPBP2, and connects out to PubMed, human chromosome 17 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 17.
Vinony links it to 5 Wikipedia language editions.
Gene data
APPBP2- Name
- amyloid beta precursor protein binding protein 2
- Type
- protein-coding
- Position
- 60,443,158–60,526,242 (−)
- Aliases
- APP-BP2, HS.84084, PAT1
- Ensembl
- ENSG00000062725
- RefSeq RNA
- NM_001282476.2, NM_006380.5, XM_047435116.1, XM_047435118.1, XM_054314702.1
- RefSeq protein
- NP_001269405.1, NP_006371.2, XP_047291072.1, XP_047291074.1, XP_054170677.1
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
amyloid beta precursor protein binding protein 2
- Symbol
- APPBP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:60,443,158-60,526,242
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 31378
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10513
- genomic end
- 60526242
- genomic start
- 60443158
- chromosome
- human chromosome 17
- cytogenetic location
- 17q23.2
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Interactions
- References
- External links
- Further reading
Amyloid protein-binding protein 2 is a protein that in humans is encoded by the APPBP2 gene.
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene.
Excerpted from Wikipedia’s “APPBP2” article, available under the CC BY-SA 4.0 licence.