PTBP2
Sign in to saveAlso known as PTBLP, brPTB, nPTB, polypyrimidine tract binding protein 2
Polypyrimidine tract binding protein 2, also known as PTBP2, is a protein which in humans is encoded by the PTBP2 gene.
Gene data
PTBP2- Name
- polypyrimidine tract binding protein 2
- Type
- protein-coding
- Aliases
- PTBLP, brPTB, nPTB
The protein encoded by this gene binds to intronic polypyrimidine clusters in pre-mRNA molecules and is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein (PTB) but most of its isoforms are expressed primarily in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].
via MyGene.info
Gene · Ensembl
polypyrimidine tract binding protein 2
- Symbol
- PTBP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:96,721,284-96,823,738
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 23162
- exact match
- identifiers.org/ncbigene/58155
- genomic start
- 97187221
- genomic end
- 97289294
- cytogenetic location
- 1p21.3
Sources (3)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- Function
- References
Polypyrimidine tract binding protein 2, also known as PTBP2, is a protein which in humans is encoded by the PTBP2 gene.
== Function == The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract-binding protein PTBP1 but it is expressed primarily in the brain.