PTH2

Also known as TIP39, parathyroid hormone 2

Tuberoinfundibular peptide of 39 residues is a protein that in humans is encoded by the PTH2 gene.

In the Vinony graph

Vinony's link graph records 2 inbound references to PTH2, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 19.

Vinony links it to 6 Wikipedia language editions.

Gene data

PTH2

Name: parathyroid hormone 2
Type: protein-coding
Position: 49,422,419–49,423,660 (−)
Aliases: TIP39
Ensembl: ENSG00000142538
RefSeq RNA: NM_178449.4
RefSeq protein: NP_848544.1

This gene encodes the precursor of a peptide hormone that shares sequence similarity with the parathyroid hormone. This gene is expressed in various regions of the brain where it plays a role in the release of pituitary hormones, anxiety and nociception. The encoded precursor protein is proteolytically processed to generate the biologically active neuropeptide. [provided by RefSeq, Jul 2015].

Gene Ontology

Biological process

neuropeptide signaling pathway

Molecular function

protein binding

Cellular component

extracellular region extracellular region

Pathways

Neuroactive ligand-receptor interaction - Homo sapiens (human)Signal Transduction Signaling by GPCR Class B/2 (Secretin family receptors)GPCR downstream signalling G alpha (s) signalling events GPCR ligand binding

via MyGene.info

Gene · Ensembl

parathyroid hormone 2

Symbol: PTH2
Biotype: Protein coding
Organism: Homo sapiens
Location: 19:49,422,419-49,423,660
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 14235
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/113091
genomic end: 49926698
genomic start: 49925671
chromosome: human chromosome 19
cytogenetic location: 19q13.33
expressed in: occipital lobe

Sources (3)

via Wikidata · CC0

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Encyclopedic overview

2 sections

Contents

References
Further reading

Tuberoinfundibular peptide of 39 residues is a protein that in humans is encoded by the PTH2 gene.

TIP39 is related to parathyroid hormone (PTH; MIM 168450) and PTH-related protein (PTHRP; MIM 168470) and is a ligand for PTH receptor-2 (PTHR2; MIM 601469) (John et al., 2002).[supplied by OMIM]

Excerpted from Wikipedia’s “PTH2” article, available under the CC BY-SA 4.0 licence.