APLP1
Sign in to saveAlso known as APLP, amyloid beta precursor like protein 1
Amyloid precursor like protein 1, also known as APLP1, is a protein encoded by the APLP1 gene in humans. APLP1 along with APLP2 are important modulators of glucose and insulin homeostasis.
Gene data
APLP1- Name
- amyloid beta precursor like protein 1
- Type
- protein-coding
- Aliases
- APLP
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
amyloid beta precursor like protein 1
- Symbol
- APLP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:35,867,899-35,879,803
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- 3qmk.png
Show 5 more facts
- HomoloGene ID
- 68447
- exact match
- identifiers.org/ncbigene/333
- genomic end
- 35879792
- genomic start
- 36358801
- cytogenetic location
- 19q13.12
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- References
- Further reading
- External links
Amyloid precursor like protein 1, also known as APLP1, is a protein encoded by the APLP1 gene in humans. APLP1 along with APLP2 are important modulators of glucose and insulin homeostasis.
== Function ==