AP2A2
Sign in to saveAlso known as ADTAB, CLAPA2, HIP-9, HIP9, HYPJ, adaptor related protein complex 2 alpha 2 subunit, adaptor related protein complex 2 subunit alpha 2
AP-2 complex subunit alpha-2 is a protein that in humans is encoded by the AP2A2 gene.
Gene data
AP2A2- Name
- adaptor related protein complex 2 subunit alpha 2
- Type
- protein-coding
- Position
- 924,881–1,012,245 (+)
- Aliases
- ADTAB, CLAPA2, HIP-9, HIP9, HYPJ
- Ensembl
- ENSG00000280759
- RefSeq RNA
- NM_001242837.2, NM_012305.4, NR_144509.2, NR_144510.2, XM_011519929.2
- RefSeq protein
- NP_001229766.1, NP_036437.1, XP_011518231.1, XP_011518232.1, XP_047282435.1
The protein encoded by this gene is a subunit of the AP-2 adaptor protein complex, which is involved in linking lipid and protein membrane components with the clathrin lattice. This interaction supports the formation of clathrin-coated vesicles, and the encoded subunit aids in the process by binding polyphosphoinositide-containing lipids in the cell membrane. [provided by RefSeq, Nov 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
adaptor related protein complex 2 subunit alpha 2
- Symbol
- AP2A2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HSCHR11_3_CTG1:3,478-81,830
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein AP2A2 PDB 1b9k.png
Show 5 more facts
- HomoloGene ID
- 5335
- exact match
- identifiers.org/ncbigene/161
- genomic start
- 924881
- genomic end
- 1012239
- cytogenetic location
- 11p15.5
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Interactions
- References
- Further reading
- External links
AP-2 complex subunit alpha-2 is a protein that in humans is encoded by the AP2A2 gene.
== Interactions ==