AP2A2

Also known as ADTAB, CLAPA2, HIP-9, HIP9, HYPJ, adaptor related protein complex 2 alpha 2 subunit, adaptor related protein complex 2 subunit alpha 2

AP-2 complex subunit alpha-2 is a protein that in humans is encoded by the AP2A2 gene.

Gene data

AP2A2

Name: adaptor related protein complex 2 subunit alpha 2
Type: protein-coding
Position: 924,881–1,012,245 (+)
Aliases: ADTAB, CLAPA2, HIP-9, HIP9, HYPJ
Ensembl: ENSG00000280759
RefSeq RNA: NM_001242837.2, NM_012305.4, NR_144509.2, NR_144510.2, XM_011519929.2
RefSeq protein: NP_001229766.1, NP_036437.1, XP_011518231.1, XP_011518232.1, XP_047282435.1

The protein encoded by this gene is a subunit of the AP-2 adaptor protein complex, which is involved in linking lipid and protein membrane components with the clathrin lattice. This interaction supports the formation of clathrin-coated vesicles, and the encoded subunit aids in the process by binding polyphosphoinositide-containing lipids in the cell membrane. [provided by RefSeq, Nov 2016].