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GeneQ18039698· pop 6· linked from 5 articles

Also known as epsin 1

Epsin-1 is a protein that in humans is encoded by the EPN1 gene.

Gene data

EPN1
Name
epsin 1
Type
protein-coding

This gene encodes a member of the epsin protein family. The encoded protein binds clathrin and is involved in the endocytosis of clathrin-coated vesicles. Loss of function of this gene is associated with reduced tumor growth and progression in certain cancer types. [provided by RefSeq, Mar 2016].

via MyGene.info

Gene · Ensembl

epsin 1

Symbol
EPN1
Biotype
Protein coding
Organism
Homo sapiens
Location
19:55,675,109-55,709,858
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
Protein EPN1 PDB 1edu.png
Show 5 more facts
HomoloGene ID
32172
genomic end
56221224
genomic start
56186592
cytogenetic location
19q13.42
Sources (3)

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~1 min read

Article

3 sections
Contents
  • Interactions
  • References
  • Further reading

Epsin-1 is a protein that in humans is encoded by the EPN1 gene.

EPN1 is an endocytic accessory protein that interacts with EPS15 (MIM 600051), the alpha subunit of the clathrin adaptor AP2 (AP2A1; MIM 601026), and clathrin (see MIM 118960), as well as with other accessory proteins for the endocytosis of clathrin-coated vesicles.[supplied by OMIM]

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