EPN1
Sign in to saveAlso known as epsin 1
Epsin-1 is a protein that in humans is encoded by the EPN1 gene.
Gene data
EPN1- Name
- epsin 1
- Type
- protein-coding
This gene encodes a member of the epsin protein family. The encoded protein binds clathrin and is involved in the endocytosis of clathrin-coated vesicles. Loss of function of this gene is associated with reduced tumor growth and progression in certain cancer types. [provided by RefSeq, Mar 2016].
via MyGene.info
Gene · Ensembl
epsin 1
- Symbol
- EPN1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:55,675,109-55,709,858
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein EPN1 PDB 1edu.png
Show 5 more facts
- exact match
- identifiers.org/ncbigene/29924
- HomoloGene ID
- 32172
- genomic end
- 56221224
- genomic start
- 56186592
- cytogenetic location
- 19q13.42
Sources (3)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Interactions
- References
- Further reading
Epsin-1 is a protein that in humans is encoded by the EPN1 gene.
EPN1 is an endocytic accessory protein that interacts with EPS15 (MIM 600051), the alpha subunit of the clathrin adaptor AP2 (AP2A1; MIM 601026), and clathrin (see MIM 118960), as well as with other accessory proteins for the endocytosis of clathrin-coated vesicles.[supplied by OMIM]