EPS15
Sign in to saveAlso known as AF-1P, AF1P, MLLT5, epidermal growth factor receptor pathway substrate 15
Epidermal growth factor receptor substrate 15 is a protein that in humans is encoded by the EPS15 gene.
Gene data
EPS15- Name
- epidermal growth factor receptor pathway substrate 15
- Type
- protein-coding
- Aliases
- AF-1P, AF1P, MLLT5
This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009].
via MyGene.info
Gene · Ensembl
epidermal growth factor receptor pathway substrate 15
- Symbol
- EPS15
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:51,354,263-51,519,387
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein EPS15 PDB 1c07.png
Show 5 more facts
- HomoloGene ID
- 128359
- exact match
- identifiers.org/ncbigene/2060
- genomic end
- 51519266
- genomic start
- 51819935
- cytogenetic location
- 1p32.3
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Epidermal growth factor receptor substrate 15 is a protein that in humans is encoded by the EPS15 gene.
== Function ==