NUMB
Sign in to saveAlso known as C14orf41, S171, c14_5527, NUMB, endocytic adaptor protein, NUMB endocytic adaptor protein
protein-coding gene in the species Homo sapiens
Gene data
NUMB- Name
- NUMB endocytic adaptor protein
- Type
- protein-coding
- Aliases
- C14orf41, S171, c14_5527
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016].
via MyGene.info
Gene · Ensembl
NUMB endocytic adaptor protein
- Symbol
- NUMB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:73,274,146-73,466,167
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein NUMB PDB 1wj1.png
Show 5 more facts
- HomoloGene ID
- 2775
- cytogenetic location
- 14q24.2-q24.3
- exact match
- identifiers.org/ncbigene/8650
- genomic end
- 73458617
- genomic start
- 73741815
via Wikidata · CC0
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