Also known as CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2
Dihydropyrimidinase-related protein 2 is an enzyme that in humans is encoded by the DPYSL2 gene.
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].
via MyGene.info
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Dihydropyrimidinase-related protein 2 is an enzyme that in humans is encoded by the DPYSL2 gene.
==Interactions== DPYSL2 has been shown to interact with CRMP1, Adaptor-related protein complex 2, alpha 1 and NUMB.
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).