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GeneQ18051579· pop 5· linked from 84 articles

Also known as CDGF13, CDHF13, HYPT6, LAH, desmoglein 4

Desmoglein-4 is a protein that in humans is encoded by the DSG4 gene.

Gene data

DSG4
Name
desmoglein 4
Type
protein-coding
Aliases
CDGF13, CDHF13, HYPT6, LAH

This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth. [provided by RefSeq, May 2016].

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Gene · Ensembl

desmoglein 4

Symbol
DSG4
Biotype
Protein coding
Organism
Homo sapiens
Location
18:31,376,777-31,414,979
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
65341
genomic start
28956740
genomic end
28994875
cytogenetic location
18q12.1
Sources (3)

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Contents
  • See also
  • References
  • Further reading

Desmoglein-4 is a protein that in humans is encoded by the DSG4 gene.

== See also == List of conditions caused by problems with junctional proteins

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