DRG2

Also known as developmentally regulated GTP binding protein 2

Developmentally-regulated GTP-binding protein 2 is a protein that in humans is encoded by the DRG2 gene.

In the Vinony graph

Vinony's link graph records 2 inbound references to DRG2, and connects out to PubMed, human chromosome 17 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 17.

Vinony links it to 6 Wikipedia language editions.

Gene data

DRG2

Name: developmentally regulated GTP binding protein 2
Type: protein-coding
Position: 18,087,876–18,107,979 (+)
Ensembl: ENSG00000108591
RefSeq RNA: NM_001330144.2, NM_001388.5, XM_005256499.4, XM_005256500.3, XM_011523704.3
RefSeq protein: NP_001317073.1, NP_001379.1, XP_005256556.1, XP_005256557.1, XP_011522006.1

This gene encodes a GTP-binding protein known to function in the regulation of cell growth and differentiation. Read-through transcripts containing this gene and a downstream gene have been identified, but they are not thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jan 2012].

Gene Ontology

Biological process

cytoplasmic translation signal transduction

Molecular function

RNA binding GTPase activity GTPase activity protein binding GTP binding GTP binding GTP binding

Cellular component

nucleus nucleus cytoplasm cytoplasm cytoplasm cytosol cytosol membrane

Pathways

Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation Metabolism of proteins Post-translational protein modification Protein hydroxylation

via MyGene.info

Gene · Ensembl

developmentally regulated GTP binding protein 2

Symbol: DRG2
Biotype: Protein coding
Organism: Homo sapiens
Location: 17:18,087,876-18,107,979
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 1061
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/1819
genomic end: 18107970
genomic start: 18087892
chromosome: human chromosome 17
cytogenetic location: 17p11.2
expressed in: canal of the cervix

Sources (4)

via Wikidata · CC0

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Encyclopedic overview

2 sections

Contents

References
Further reading

Developmentally-regulated GTP-binding protein 2 is a protein that in humans is encoded by the DRG2 gene.

The DRG2 gene encodes the developmentally regulated GTP-binding protein 2, a name derived from the fact that it shares significant similarity to known GTP-binding proteins. DRG2 was identified because it is expressed in normal fibroblasts but not in SV40-transformed fibroblasts. Read-through transcripts containing this gene and a downstream gene have been identified, but they are not thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome 17.

Excerpted from Wikipedia’s “DRG2” article, available under the CC BY-SA 4.0 licence.