SGSM2
Sign in to saveAlso known as RUTBC1, small G protein signaling modulator 2
Small G protein signaling modulator 2 is a protein that in humans is encoded by the SGSM2 gene.
Gene data
SGSM2- Name
- small G protein signaling modulator 2
- Type
- protein-coding
- Aliases
- RUTBC1
The protein encoded by this gene is a GTPase activator with activity towards RAB32 and RAB33B, which are regulators of membrane trafficking. The encoded protein inactivates RAB32 and can bind RAB9A-GTP, a protein required for RAB32 activation. [provided by RefSeq, Oct 2016].
via MyGene.info
Gene · Ensembl
small G protein signaling modulator 2
- Symbol
- SGSM2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:2,337,488-2,381,058
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 14780
- exact match
- identifiers.org/ncbigene/9905
- genomic end
- 2284352
- genomic start
- 2240792
- cytogenetic location
- 17p13.3
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Clinical relevance
- References
- Further reading
Small G protein signaling modulator 2 is a protein that in humans is encoded by the SGSM2 gene.
==Clinical relevance== In a recent genome-wide association study, this gene has been associated with fasting glucose traits, type 2 diabetes and obesity.