IGFBP2

Name

insulin like growth factor binding protein 2

Type

protein-coding

Position

216,632,828–216,664,441 (+)

Aliases

IBP2, IGF-BP53

Ensembl

ENSG00000115457

RefSeq RNA

NM_000597.3, NM_001313990.2, NM_001313992.2, NM_001313993.2

RefSeq protein

NP_000588.3, NP_001300919.1, NP_001300921.1, NP_001300922.1

The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene. [provided by RefSeq, Sep 2015].

via MyGene.info

Gene · Ensembl

insulin like growth factor binding protein 2

Symbol

IGFBP2

Biotype

Protein coding

Organism

Homo sapiens

Location

2:216,632,828-216,664,454

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Image

Protein IGFBP2 PDB 2h7t.png

via Wikidata · CC0