IGFALS
Sign in to saveAlso known as ALS, ACLSD, insulin like growth factor binding protein acid labile subunit
Insulin-like growth factor binding protein, acid labile subunit, also known as IGFALS, is a protein which in humans is encoded by the IGFALS gene.
Gene data
IGFALS- Name
- insulin like growth factor binding protein acid labile subunit
- Type
- protein-coding
- Aliases
- ACLSD, ALS
The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
via MyGene.info
Gene · Ensembl
insulin like growth factor binding protein acid labile subunit
- Symbol
- IGFALS
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:1,790,227-1,794,971
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 37987
- exact match
- identifiers.org/ncbigene/3483
- genomic end
- 1844972
- genomic start
- 1840414
- cytogenetic location
- 16p13.3
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Clinical significance
- Interactions
- References
- Further reading
Insulin-like growth factor binding protein, acid labile subunit, also known as IGFALS, is a protein which in humans is encoded by the IGFALS gene.
== Function ==