IGFBP5
Sign in to saveAlso known as IBP5, insulin like growth factor binding protein 5
Insulin-like growth factor-binding protein 5 (IBF-5) is a protein that in humans is encoded by the IGFBP5 gene. An IGFBP5 gene was recently identified as being important for adaptation to varying water salinity in fish.
Gene data
IGFBP5- Name
- insulin like growth factor binding protein 5
- Type
- protein-coding
- Position
- 216,672,105–216,695,549 (−)
- Aliases
- IBP5
- Ensembl
- ENSG00000115461
- RefSeq RNA
- NM_000599.4
- RefSeq protein
- NP_000590.1
Enables insulin-like growth factor I binding activity. Involved in several processes, including cellular response to cAMP; regulation of smooth muscle cell migration; and regulation of smooth muscle cell proliferation. Part of insulin-like growth factor ternary complex. Biomarker of pulmonary fibrosis. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
insulin like growth factor binding protein 5
- Symbol
- IGFBP5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:216,672,105-216,695,549
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein IGFBP5 PDB 1boe.png
Show 6 more facts
- HomoloGene ID
- 56489
- genomic end
- 216695549
- exact match
- identifiers.org/ncbigene/3488
- genomic start
- 217536828
- cytogenetic location
- 2q35
- Commons category
- Insulin-like growth factor-binding protein-5 (IGFBP-5)
Sources (4)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
Insulin-like growth factor-binding protein 5 (IBF-5) is a protein that in humans is encoded by the IGFBP5 gene. An IGFBP5 gene was recently identified as being important for adaptation to varying water salinity in fish.
==References==