DAZAP2
Sign in to saveAlso known as PRTB, DAZ associated protein 2
DAZ-associated protein 2 is a protein that in humans is encoded by the DAZAP2 gene.
Gene data
DAZAP2- Name
- DAZ associated protein 2
- Type
- protein-coding
- Aliases
- PRTB
This gene encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
via MyGene.info
Gene · Ensembl
DAZ associated protein 2
- Symbol
- DAZAP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:51,238,724-51,272,164
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 8038
- exact match
- identifiers.org/ncbigene/9802
- genomic end
- 51665146
- genomic start
- 51238724
- cytogenetic location
- 12q13.13
Sources (4)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
DAZ-associated protein 2 is a protein that in humans is encoded by the DAZAP2 gene.
== Function ==