DCP2
Sign in to saveAlso known as NUDT20, decapping mRNA 2
mRNA-decapping enzyme 2 is a protein that in humans is encoded by the DCP2 gene.
Gene data
DCP2- Name
- decapping mRNA 2
- Type
- protein-coding
- Aliases
- NUDT20
The protein encoded by this gene is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). It removes the 7-methyl guanine cap structure from mRNA, prior to its degradation from the 5' end. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011].
via MyGene.info
Gene · Ensembl
decapping mRNA 2
- Symbol
- DCP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:112,976,702-113,028,477
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 13968
- exact match
- identifiers.org/ncbigene/167227
- genomic end
- 113022195
- genomic start
- 112312399
- cytogenetic location
- 5q22.2
Sources (4)
via Wikidata · CC0
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- Further reading
mRNA-decapping enzyme 2 is a protein that in humans is encoded by the DCP2 gene.
DCP2 is a key component of an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005).[supplied by OMIM]