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GeneQ18030599· pop 5· linked from 36 articles

Also known as Cwc1, PRL1, PRP46, PRPF46, TANGO4, pleiotropic regulator 1

Pleiotropic regulator 1 is a protein that in humans is encoded by the PLRG1 gene.

Gene data

PLRG1
Name
pleiotropic regulator 1
Type
protein-coding
Aliases
Cwc1, PRL1, PRP46, PRPF46, TANGO4

This gene encodes a core component of the cell division cycle 5-like (CDC5L) complex. The CDC5L complex is part of the spliceosome and is required for pre-mRNA splicing. The encoded protein plays a critical role in alternative splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].

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Gene · Ensembl

pleiotropic regulator 1

Symbol
PLRG1
Biotype
Protein coding
Organism
Homo sapiens
Location
4:154,535,005-154,550,415
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
2004
genomic end
154550400
genomic start
154535005
cytogenetic location
4q31.3
Sources (3)

via Wikidata · CC0

~1 min read

Article

3 sections
Contents
  • Interactions
  • References
  • Further reading

Pleiotropic regulator 1 is a protein that in humans is encoded by the PLRG1 gene.

==Interactions== PLRG1 has been shown to interact with CDC5L.

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