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GeneQ17859961· pop 7· linked from 112 articles

Also known as CAD11, CDHOB, OB, OSF-4, cadherin 11, ESWS, TBHS2

Cadherin-11 is a protein that in humans is encoded by the CDH11 gene.

Gene data

CDH11
Name
cadherin 11
Type
protein-coding
Position
64,943,753–65,126,112 (−)
Aliases
CAD11, CDHOB, ESWS, OB, OSF-4, TBHS2
RefSeq RNA
NM_001308392.2, NM_001330576.2, NM_001797.4, NM_033664.1, XM_047433486.1
RefSeq protein
NP_001295321.1, NP_001317505.1, NP_001788.2, XP_047289442.1, XP_054235325.1

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

cadherin 11

Symbol
CDH11
Biotype
Protein coding
Organism
Homo sapiens
Location
16:64,943,753-65,126,112
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
Protein CDH11 PDB 2a4c.png
Show 6 more facts
HomoloGene ID
1361
genomic end
65160015
genomic start
64977656
cytogenetic location
16q21
Commons category
Cadherin-11
Sources (3)

via Wikidata · CC0

~1 min read

Article

7 sections
Contents
  • Function
  • Relevance to cancer
  • Drug interactions
  • Interactions
  • References
  • Further reading
  • External links

Cadherin-11 is a protein that in humans is encoded by the CDH11 gene.

== Function ==

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