CDH11
Sign in to saveAlso known as CAD11, CDHOB, OB, OSF-4, cadherin 11, ESWS, TBHS2
Cadherin-11 is a protein that in humans is encoded by the CDH11 gene.
Gene data
CDH11- Name
- cadherin 11
- Type
- protein-coding
- Position
- 64,943,753–65,126,112 (−)
- Aliases
- CAD11, CDHOB, ESWS, OB, OSF-4, TBHS2
- Ensembl
- ENSG00000140937
- RefSeq RNA
- NM_001308392.2, NM_001330576.2, NM_001797.4, NM_033664.1, XM_047433486.1
- RefSeq protein
- NP_001295321.1, NP_001317505.1, NP_001788.2, XP_047289442.1, XP_054235325.1
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
cadherin 11
- Symbol
- CDH11
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:64,943,753-65,126,112
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CDH11 PDB 2a4c.png
Show 6 more facts
- HomoloGene ID
- 1361
- exact match
- identifiers.org/ncbigene/1009
- genomic end
- 65160015
- genomic start
- 64977656
- cytogenetic location
- 16q21
- Commons category
- Cadherin-11
Sources (3)
via Wikidata · CC0
~1 min read
Article
7 sectionsContents
- Function
- Relevance to cancer
- Drug interactions
- Interactions
- References
- Further reading
- External links
Cadherin-11 is a protein that in humans is encoded by the CDH11 gene.
== Function ==